LLY is seeing a softer-than-expected early rollout for its oral obesity pill Foundayo as competition intensifies in the rapidly expanding GLP-1 weight-loss market.
According to prescription tracking data cited by Reuters, Foundayo generated 7,335 prescriptions during its fourth week on the U.S. market. That trails significantly behind rival NVO oral Wegovy, which recorded 28,515 prescriptions in its own fourth week following launch earlier this year.
Novo Nordisk gained an important first-mover advantage after introducing oral Wegovy in January, roughly three months before Lilly launched Foundayo in April. Analysts believe the timing difference may be playing a major role in shaping early physician adoption and patient awareness.
RBC Capital Markets analyst Trung Huynh reportedly said Foundayo’s prescription growth will need to accelerate substantially to meet Wall Street sales expectations. Analysts estimate the drug may require roughly 22,000 weekly prescriptions to achieve consensus forecasts of approximately $160 million in second-quarter revenue.
Despite the slower commercial launch, Foundayo demonstrated strong clinical performance during late-stage trials. Patients taking the highest dose while remaining on therapy lost an average of 27.3 pounds, or 12.4% of body weight, compared with only 2.2 pounds for placebo participants. The treatment also improved several cardiovascular risk markers, including blood pressure, triglycerides, cholesterol levels, and waist circumference.
The broader obesity-drug market remains one of the fastest-growing areas in global healthcare. Oral GLP-1 therapies are viewed as a major next-generation opportunity because they eliminate injections, potentially improving convenience, accessibility, and long-term patient adherence.
Investor sentiment around LLY cooled slightly following the prescription data. Retail trader sentiment on Stocktwits reportedly shifted from bullish to neutral territory over the past 24 hours as investors reassessed near-term adoption trends for Foundayo.
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